Neutron beam production device for cancer therapy
Boron Neutron Capture Therapy (BNCT) is a type of experimental radiotherapy against cancer, with the uniqueness of being selective at the cellular level. It is based on the irradiation of the patient with neutrons, who has previously been administered a boron compound. Boron binds preferentially to cancer cells, so that when a neutron interacts with it, a nuclear reaction occurs that destroys or severely damages the cancer cell, leaving adjacent tissue cells with little damage.
In order to put this therapy into practice, it is necessary to have a neutron beam with specific qualities. To date, the energy sources used (nuclear reactors, low-energy, high-intensity accelerators) and the production reactions tested have resulted in higher energies than is required in a BNCT treatment. Therefore, a device (BSA) is necessary that adapts the neutrons produced to the therapeutic needs.
The invention consists of a device through which a proton beam is inserted, which interacts with a target to generate a neutron beam, a moderator that allows the neutrons to be brought up to energies in the epithermal range and a filtering stage that allows reducing the fast neutrons, thermal neutrons and gamma radiation.
After comparing the values obtained with those recommended by the International Atomic Energy Organization (IAEA) and with two of the main BNCT facilities (the FiR-1 reactor in Helsinki, currently dismantled, and the C-BENS in Kyoto) it is demonstrated that, thanks to the filtering stage, the device presented improves the previous designs and would be the answer to the problems and needs existing in the market.
Advantages and Benefits
Most suitable range of energies.
Less risk of side effects.
Greater security
Larger efficacy in treatment.
Competitive cost. It requires fewer materials.
Necessary facilities: highlight that it is easier to locate next to hospitals than other devices.
Seeking...
License agreement and exploitation and/or collaboration.
Information
Sectors of application: Medicine, pharmacy, healthcare
Stage of development: Patent in process. Priority date: 09/08/2020. Application number: P202030854
Owner: University of Granada.